Bradykinin是一个英文词汇，它来源于希腊语和拉丁语，意思是“慢激肽”。在生理学和医学中，它是一种由血管舒张素和水解酶激活的生物活性肽，是许多生理过程的组成部分。
以下是一篇关于Bradykinin的英文范文，供您参考：
Title: Bradykinin: An Important Mediator of Blood Coagulation and Vasodilation
Bradykinin, a peptide hormone, plays a crucial role in blood coagulation and vasodilation. It is produced by the enzymatic activation of the precursor kininogen by the protease kallikrein. Upon release into the bloodstream, bradykinin binds to specific receptors on the surface of cells, triggering a series of physiological responses.
One of the most prominent effects of bradykinin is its ability to induce vasodilation, which promotes blood flow and enhances tissue oxygenation. This effect is mediated by bradykinin B2 receptors, which are expressed in vascular smooth muscle cells. When bradykinin binds to these receptors, they become activated, leading to the relaxation of the surrounding smooth muscle cells and an increase in blood flow.
In addition to its role in vasodilation, bradykinin also plays a key role in blood coagulation. It acts as a procoagulant factor, stimulating the formation of fibrin from fibrinogen and promoting platelet aggregation. These effects are mediated by bradykinin B1 receptors, which are expressed on platelets and endothelial cells.
Bradykinin is also involved in the regulation of inflammatory responses, acting as a potent chemoattractant for neutrophils and other immune cells. It promotes the release of inflammatory cytokines and increases vascular permeability, leading to edema and other inflammatory symptoms.
Overall, bradykinin plays a crucial role in maintaining homeostasis in the body through its effects on blood coagulation, vasodilation, and inflammatory responses. Understanding its role and regulation is essential for developing effective therapeutic strategies for various diseases.
Bradykinin是一个英文单词，意思是缓激肽。缓激肽是一种生物活性肽，在体内由激肽原酶与促激肽释放酶（即舒缓激肽释放酶）在组织液中通过水解作用而形成，主要参与局部和全身的生理性调节。缓激肽具有舒张血管、促进血小板聚集和促进中性粒细胞聚集的作用，在心血管系统、炎症反应、神经调节以及肿瘤的发生与发展等方面发挥着重要作用。
以下是一篇关于bradykinin的英文范文，希望对您有帮助：
Title: Bradykinin: An Important Mediator in the Body's Inflammatory Response
Abstract:
Bradykinin, a biologically active peptide, is formed through the enzymatic hydrolysis of kinins. It plays a crucial role in the inflammatory response by inducing pain, vasodilation, and increased vascular permeability. Bradykinin is a key mediator in various diseases such as cardiovascular disorders, psoriasis, and inflammatory bowel disease. Understanding the role of bradykinin and its interactions with other inflammatory mediators is crucial for the development of effective therapeutic strategies.
Keywords:
Bradykinin, kinins, inflammatory response, cardiovascular disorders, psoriasis, inflammatory bowel disease
正文:
Bradykinin is a peptide that plays a crucial role in the inflammatory response. It is formed through the enzymatic hydrolysis of kinins, a family of peptides that also includes kallidin and substance P. Bradykinin is released from its precursor protein upon tissue damage or during inflammatory processes, and it acts on specific receptors to induce various physiological effects.
One of the main effects of bradykinin is the induction of pain. It acts on the peripheral nervous system to stimulate pain receptors and generate pain signals that are transmitted to the brain. In addition to pain, bradykinin also causes vasodilation and increased vascular permeability, which are important for the recruitment of immune cells to the site of injury or infection. These effects are mediated by bradykinin B2 receptors, which are expressed on various cell types, including endothelial cells, smooth muscle cells, and immune cells.
Bradykinin is a key mediator in various diseases, including cardiovascular disorders, psoriasis, and inflammatory bowel disease. Understanding its role in these diseases and its interactions with other inflammatory mediators is crucial for the development of effective therapeutic strategies. For example, bradykinin receptor antagonists have been used as anti-inflammatory drugs in clinical practice for decades.
In conclusion, bradykinin plays a crucial role in the inflammatory response and is involved in various diseases. Understanding its role and interactions with other mediators is essential for developing new therapeutic strategies for these diseases.
Bradykinin的意思是缓激肽。
在英文范文里，它可能表示一种参与人体生理调节的物质，特别是在血管舒张方面。